The nonallosteric mechanism of enzyme activity regulation. Is it the only true mechanism?
نویسنده
چکیده
The nonallosteric regulation mechanism of enzyme reaction velocity assumes that the substrate and enzyme interact via a metal cation and form simple and mixed, mono- and multi-nuclear complexes. A solution of equations for individual cases gives a function of initial reaction velocity at any given substrate or modifier concentration. This function can describe kinetic effects that are considered allosteric, as well as phenomena omitted by commonly-accepted models.
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ورودعنوان ژورنال:
- Cellular & molecular biology letters
دوره 8 1 شماره
صفحات -
تاریخ انتشار 2003